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Microscopy: A sharper, clearer view
‘X-ray vision’ may be the stuff of comic books, but scientists have identified various approaches that turn this fanciful concept into a real-world tool. Chemical-based tissue-clearing techniques render opaque organs like the brain and bones—or even entire animals—clear as glass, giving scientists a literal window onto cellular activity deep within. Some iterations of these methods even induce proportional expansion of cleared specimens by up to 20-fold, allowing conventional microscopes to tease apart fine details that once required cutting-edge technology.
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