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Cancer: Neighborhood watch
Cancer biologists have historically focused their attention on tumor cells while paying little mind to the non-cancerous cells surrounding them. In the age of immunotherapy, this is no longer an option, as it has become clear that immune cells in the greater ‘tumor microenvironment’ (TME) can play a decisive role in determining how patients respond to immunity-stimulating treatments. Powerful tools have been developed for mapping and characterizing the TME, yielding insights that may guide smarter, more effective strategies for diagnosis and treatment.
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