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Specialty probes for imaging at super-resolution
Fluorescent proteins and dyes are crucial tools in confocal microscopy and for imaging with super-resolution techniques. Specialty probes are needed to categorize events inside cells and for localizing single molecules.
These probes might be synthesized dyes or they can be engineered fluorescent proteins, for example photoactivatable or photoswitchable fluorescent proteins. To get these probes to work well is both an art and a science. Labs don’t just want probes to work well in vitro, they want them to be useful in living cells.
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