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Nature Methods Technology Feature – Genomics

Booking Deadline Jan 16
Publication Name:
Nature Methods
Materials Due:
Jan 17
Publication Date:
Feb 01

Don’t miss this opportunity to target an engaged audience interested in Genomics!

Genomics: embryo-editing

Embryo-editing has been in the news. A research team in China appears to have committed a research ethics breach and brought gene-edited newborns to term. This approach potentially derails the gene-editing field. But the hope is that it does not.

There is much serious, ethical work ongoing in gene-editing, including the gene-editing of embryos, both mouse and human embryos. This technology feature looks at some of this serious work underway in labs. CRISPR-Cas9-mediated gene-editing tools as well as base-editing tools are being engineered in many ways, for example to better their efficiency and accuracy. This basic research is needed to prepare the road for potential clinical applications of these techniques.

This Technology Feature will cover:

  • DNA repair mechanisms in embryos
  • Sources of variability in gene-editing experiments
  • Approaches underway to mature gene-editing

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