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Lab Animal Technology Feature – Emerging models

Booking Deadline Jul 09
Publication Name:
Lab Animal
Materials Due:
Jul 10
Emerging models
Publication Date:
Aug 01

Don’t miss this opportunity to target an engaged audience interested in emerging models!

Emerging models: wild fishes with clinical phenotypes

Conventional laboratory species are invaluable for modeling human disease. But models they often are; in many cases, they are manipulated to mimic diseases they would not get normally. What if there were more natural options available to study a disease? Some researchers are looking to the wild for alternatives.

This Technology Feature will consider three fishes with naturally occurring phenotypes that, when found in humans, are associated with pathology. These include: Antarctic icefish, with porous bones and no red blood cells; Mexican cavefish, with unique means of energy metabolism and storage; and the killifish of the Northeast, exposed to numerous pollutants to seemingly little ill effect.

This Technology Feature Will Cover:

  • Some basic biology and natural history of these three fishes
  • How they are being used by researchers to ask questions about human health & disease
  • Considerations for collecting them in the wild and keeping them in the lab

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