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Introducing the Technology Features
These editorially-independent features, published in the Nature and Nature Methods print journals and online on nature.com, spotlight scientists, the technology, and the methods they choose – their views of what works and what does not – providing key information that scientists globally can implement in their own labs.
25 Technology Features are being published in Nature and Nature Methods throughout 2020, and in September, Nature is publishing its next Technology Feature on Reproducibility.
‘Research antibodies: Mind the validation‘
Perhaps no research reagent is more widely used, or more maligned, than antibodies. These Y-shaped proteins are used to detect other proteins in cells and tissues. They are ubiquitous in research and testing laboratories. Yet when an antibody designed to detect one protein actually detects something else, errors can multiply. The key is validation: identifying multiple candidate antibodies against a given protein target, checking what testing has already been performed, and performing the positive and negative controls relevant for your laboratory.
The Technology Feature will cover:
- Why antibodies fail
- Validation strategies
- How CRISPR can help
Publication & Publication Date: Nature, September 10, 2020
Ad Booking Deadline: August 25, 2020
Ad Materials Due: August 27, 2020
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Interested in our upcoming Technology Features? View the Nature and Nature Methods 2020 calendars.
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